Menu Close
cropped-evoke-wellness-favicon-logo-512x512-1-1.png

Build a foundation for lasting recovery

The Adverse Effects of Trazodone: What You Should Know

As you consider treatment options for depression or insomnia, trazodone may be on your radar. While this prescription medication can be effective for some, it’s crucial to understand its potential adverse effects. Recent studies have shown that up to 40% of patients experience side effects from trazodone, ranging from mild to severe. At Evoke Wellness at Hilliard, we believe in empowering you with knowledge to make informed decisions about your health.

Together, let’s embrace the journey to recovery and the promise of a new beginning. Call us at (833) 949-1347 today or reach out online.

What is trazodone?

Trazodone is a prescription medication primarily used to treat depression. However, it is also commonly prescribed off-label as a sleep aid due to its sedating effects.

A Brief Overview

  • Trazodone belongs to the class of drugs known as serotonin antagonists and reuptake inhibitors (SARIs).
  • It works by increasing the availability of serotonin, a neurotransmitter that regulates mood, sleep, and other bodily functions.
  • Though initially developed as an antidepressant, trazodone’s strong sedative properties make it a popular choice for treating insomnia.

Usage and Effects

While effective for many, trazodone can cause adverse effects – especially when combined with other substances or taken long-term. Common side effects include:

  • Drowsiness and fatigue
  • Dizziness and headaches
  • Dry mouth
  • Constipation

More severe reactions like priapism, serotonin syndrome, and increased suicide risk in young adults have also been reported. As with any medication, it’s crucial to follow dosage instructions and be aware of potential interactions.

Common side effects of trazodone

Trazodone, a serotonin modulator commonly prescribed for insomnia and depression, comes with potential side effects patients should be aware of. While generally well-tolerated, some adverse reactions may occur.

Drowsiness & Dizziness

  • The most common side effect is drowsiness, affecting up to 30% of trazodone users according to recent studies.
  • Dizziness and lightheadedness can also occur, making it crucial to avoid driving or operating heavy machinery until adjusting to the medication.

Dry Mouth & Constipation

  • Trazodone has anticholinergic properties that may lead to dry mouth in up to 25% of patients.
  • Constipation is another common complaint, affecting around 10-15% of trazodone users. Staying hydrated and increasing fiber intake can help mitigate this.

Headaches & Nausea

  • Mild headaches have been reported by some trazodone users, though typically subsiding with continued use.
  • Nausea may occur initially but often improves over time as the body adjusts to the medication.

While most side effects are mild, severe or persistent reactions should be reported to your healthcare provider promptly. Tapering off slowly under medical supervision is recommended when discontinuing trazodone to avoid withdrawal effects.

Serious side effects of trazodone

Increased Risk of Falls

Priapism

  • In rare cases, trazodone may cause priapism – a prolonged, painful erection that can lead to permanent impotence if not treated promptly. Seek immediate medical attention if this side effect occurs.

Serotonin Syndrome

  • When combined with other serotonergic medications like certain antidepressants or migraine drugs, trazodone increases the risk of developing serotonin syndrome – a potentially life-threatening condition. Symptoms include agitation, hallucinations, coma, and other effects.

Cardiovascular Effects

  • Trazodone may cause orthostatic hypotension (sudden drop in blood pressure when standing), which increases fall risk. It can also cause arrhythmias in some patients. Those with heart disease should use caution.

What are the precautions for trazodone?

Dosage Guidelines

  • Trazodone should be taken exactly as prescribed by your healthcare provider. Do not increase or decrease the dosage without consulting them first.
  • Typically, trazodone is started at a low dose and gradually increased until the desired effect is achieved.

Potential Interactions

Trazodone can interact with certain medications, including:

  • Antidepressants
  • Blood thinners
  • Sedatives or tranquilizers
  • Drugs metabolized by certain liver enzymes

Inform your doctor about all prescription, over-the-counter, and herbal medications you are taking.

Precautions for Specific Groups

  • Pregnant or breastfeeding women should discuss the risks and benefits with their doctor before taking trazodone.
  • Older adults may be more sensitive to the sedative effects and should use caution.
  • People with liver or kidney disease may require dosage adjustments.

Monitoring

Your doctor may monitor your health regularly while taking trazodone, including:

  • Blood tests to check liver function
  • Monitoring for side effects like dizziness, drowsiness, or changes in behavior

Adhering to these precautions can help ensure the safe and effective use of trazodone.

Why is trazodone not recommended?

Dangerous Interactions

Trazodone should be used with caution due to its potential for dangerous interactions with other substances. As mentioned on the Evoke Wellness blog, it can be risky to combine trazodone with illicit drugs or certain prescription medications. Taking trazodone alongside other depressants like alcohol or opioids increases the risk of excessive sedation, respiratory depression, and other adverse effects.

Addiction Potential

While trazodone itself has a relatively low potential for abuse and addiction, misusing the medication by taking higher doses or combining it with other substances can be habit-forming. This increases the chances of developing a substance use disorder requiring professional treatment like prescription drug rehab or polysubstance abuse treatment programs.

Unpleasant Side Effects

Trazodone is known to cause side effects like drowsiness, dizziness, headaches, and nausea, especially when starting treatment or adjusting the dosage. According to Evoke Wellness, these effects can be unpleasant and may require close monitoring by a doctor. For some patients, the side effects outweigh the intended benefits of taking trazodone.

For these reasons of dangerous interactions, addiction risks, and adverse side effects, trazodone may not be recommended as a first-line treatment option compared to other antidepressant medications. Patients should carefully weigh the potential benefits and risks in consultation with their healthcare provider.

Trazodone withdrawal and addiction

Picture2 10

To minimize withdrawal risks, trazodone should be tapered off slowly under medical supervision.

Abuse Potential

While trazodone has a low potential for abuse compared to other sedatives, it can still be misused. Taking excessive doses produces a marijuana-like high. This recreational abuse increases overdose risks and adverse effects like:

  • Slurred speech
  • Drowsiness and lethargy
  • Impaired coordination
  • Irregular heart rate

Polysubstance abuse involving trazodone is also concerning. Proper addiction treatment may be required for those struggling with trazodone misuse.

Substance abuse treatment program at Evoke Wellness

At Evoke Wellness, a comprehensive approach is taken to treat substance abuse disorders through various evidence-based programs. Their treatment offerings include programs for alcohol addiction, drug addiction, heroin addiction, meth addiction, opioid addiction, cocaine addiction, fentanyl addiction, prescription drug rehab, and painkiller rehab.

Programs & Therapies

The treatment programs encompass medical detox, acute detox, residential treatment, intensive inpatient treatment, dual diagnosis treatment, and rehab aftercare. Medication-assisted treatment programs using Vivitrol, Suboxone, and Methadone are also available to aid in recovery from substance use disorders.

Evoke Wellness utilizes evidence-based therapies such as:

Specialized Care

In addition to their comprehensive programs, Evoke Wellness offers specialized care for specific populations. This includes treatment programs tailored for veterans and LGBTQ individuals seeking substance abuse treatment. Their holistic approach aims to address the unique challenges faced by these communities during the recovery process.

FAQ on Trazadone adverse effects

Common Side Effects

  • Drowsiness or sedation
  • Dizziness
  • Dry mouth
  • Headache
  • Nausea

Less Common Effects

  • Constipation
  • Blurred vision
  • Nervousness
  • Confusion or delirium (especially in the elderly)

Rare But Serious Effects

  • Abnormal heart rhythms (arrhythmias)
  • Low blood pressure (hypotension)
  • Impaired coordination and balance
  • Priapism (prolonged, painful erection)

The risk of adverse effects tends to increase with higher doses. Older adults may be more susceptible due to age-related factors. Stopping trazodone abruptly can also cause withdrawal effects like nausea, vomiting, and sweating.

Proper dosing, monitoring, and medical supervision are important to mitigate risks. Consult a doctor immediately if experiencing severe or persistent side effects. Substance abuse treatment programs and therapy can help manage any dependence issues.

Conclusion

While trazodone can be an effective treatment for depression and insomnia, you must be aware of its potential adverse effects. Recent studies show that up to 40% of patients experience side effects, with dizziness and drowsiness being most common. If you’re struggling with trazodone misuse or polysubstance abuse, professional help is available. Prescription drug rehab, substance abuse treatment programs, and drug detox can provide the support you need. Consider exploring residential treatment options, therapy programs, and rehab aftercare to build a strong foundation for recovery. Remember, your health and well-being are paramount. Consult your healthcare provider to discuss any concerns and explore alternative treatments if needed. With proper care and support, you can overcome challenges related to trazodone use and achieve lasting wellness.

Begin Your Journey with Evoke Wellness at Hilliard

If you or a loved one is considering treatment, Evoke Wellness at Hilliard invites you to contact us. Our compassionate team is ready to answer your questions, discuss your needs, and help you take the first steps toward recovery. In Hilliard, you’ll find more than just a treatment program – you’ll discover a community dedicated to your wellness and success. Together, let’s embrace the journey to recovery and the promise of a new beginning. Call us at (833) 949-1347 today or reach out online.